Showing posts with label nicotine. Show all posts
Showing posts with label nicotine. Show all posts

Monday, August 11, 2025

Announcing a New Lecture Series on Tobacco Harm Reduction

 

I am pleased to announce a new lecture series on the medical and scientific evidence for tobacco harm reduction.

This week, I am publishing “Nicotine, Correcting Misperceptions.”  The lecture is divided into an introduction and six easily digestible segments; run time and links are below. 

Nicotine, Correcting Misperceptions

Introduction     2:45  (link here)         

Comparing nicotine with caffeine, and contrasting positive and negative effects of nicotine on the brain, in the context of addiction     3:43  (link here)

Comparing nicotine delivery among combustible, smoke-free oral and aerosol tobacco and medicinal nicotine products         14:35  (link here)

Distinguishing the health effects of nicotine from those of combustible and smoke-free tobacco     14:35  (link here)

Weighing the evidence of nicotine use during pregnancy     4:00  (link here)

Investigating how the medical facts about nicotine have been exaggerated and distorted     5:00  (link here)

Valuing long-term nicotine maintenance and tobacco harm reduction     4:46  (link here)

 

You might think that you already know everything about nicotine.  So go ahead…TEST YOUR KNOWLEDGE OF NICOTINE by taking a short quiz!

You’ll get immediate feedback on your score, and the answers might prompt you to watch some of the segments.  Enjoy!

Note: While I originally created these lectures as a continuing medical education (CME) course (more information here), they do not presently convey CME credit, but are available to all who are interested in safer tobacco products for themselves, their families and friends.

I will publish the remaining topics soon.


Wednesday, April 16, 2025

Gold Rush: Measuring Nicotine Mortality by the Millimeter

 

The New Yorker magazine recently published an article, “Zyn and the New Nicotine Gold Rush,”  that included a remarkable passage from a discussion between the author and Thomas Ericsson, a former Swedish Match employee.  It perfectly describes the risks of using snus and nicotine. 

“I asked Ericsson whether he had any concerns about the possible harms of nicotine itself. ‘Of course you should have concerns,’ he told me. ‘Or you should do risk analysis.’ He walked out of the room and returned with a large ball of string. The string was exactly ninety-five metres long, each millimetre representing one of Sweden’s approximate ninety-five thousand annual deaths. Ericsson slowly unravelled the string until he reached a piece of tape representing the people who die early from smoking each year. He moved his fingers down to another marker, a few meters shorter, which represented the people who die from drinking. He continued shortening the string, indicating the number of deaths by suicide (fifteen hundred), drowning (a hundred and fifty), car accidents (two hundred), and workplace accidents (between fifty and seventy).

“‘You can ask yourself, What are Swedish people most afraid of? They’re afraid to fly. They’re afraid of wolves. They’re afraid of deer and other things,’ he said, holding a short length of string. ‘But what you should be afraid of is the wasp. It kills five to ten people every year.’ Finally, Ericsson reached the very tip of the string. While working on Nicorette, he and his colleagues did a risk-analysis calculation that estimated that fewer than two people per year would die of heart illnesses exacerbated by nicotine use. Compared with other hazards, he said, ‘this is not a big risk.’”

I have recognized the minuscule risks of snus since 1995, when I first described the Swedish experience in a peer-reviewed publication:

“Sweden has been the world's largest per capita consumer of smokeless tobacco (ST) throughout the 20th century, without a resultant oral cancer epidemic.  On the contrary, the age-adjusted mortality rate for oral cancer from 1960 to 1990 in Sweden was low and remarkably stable at 2.3 to 3.6 per 100,000 person-years.  A retrospective study of 200,000 male snuff dippers in Sweden found only one case of oral cancer per year.  This is in marked contrast to most other European countries where ST use is essentially nonexistent and where increases in oral cancer mortality have mirrored earlier increases in cigarette consumption.  The greatest increase in oral cancer mortality has occurred in France (13.4/100,000 person-years in 1955-59 to 32.3/100,000 person-years in 1985-89). 

“It is not surprising to find that Swedish lung cancer mortality rates have been the lowest in Europe over the past 40 years.  These large scale vital statistics from Sweden and France strongly support the suggestion that if tobacco is to be used, it should be in the form of ST and not cigarettes. The population that uses ST in lieu of smoking is, in effect, protected from lung cancer and other major smoking-related diseases and suffers little or no increased risk of oral cancer.” (emphasis added, references removed)

In 2004, following my research sabbatical at Sweden’s UmeÃ¥ University, I published this:

Rodu B, Cole P.  The burden of mortality from smoking: comparing Sweden with other countries in the European Union.  European Journal of Epidemiology 19: 129-131, 2004. https://www.ncbi.nlm.nih.gov/pubmed/15074568  

In that article, epidemiologist Philip Cole and I described “the mortality currently attributable to smoking in the European Union (EU), and the change that would result if all EU countries had the smoking prevalence of Sweden.  Almost 500,000 smoking-attributable deaths occur annually among men in the EU; about 200,000 would be avoided at Swedish smoking rates.”

More than 20 years after our estimates were published, the Swedish Tobacco Experience has become a Gold Rush, meaning that more people are consuming nicotine and tobacco in a safer fashion.