Showing posts with label Michael Fiore. Show all posts
Showing posts with label Michael Fiore. Show all posts

Wednesday, June 20, 2018

American Cancer Society’s Combustible Tobacco Statement Contains Falsehood



The American Cancer Society’s new position statement offering a “bold new framework” for eliminating combustible tobacco use in the U.S. (here) contains a demonstrably invalid statement: “Cigarette smoking is the leading cause of cancer mortality in the United States (1), accounting for as much as 98% of all tobacco-related deaths (2) [emphasis added].

The problem with the highlighted phrase is that no estimate of “all tobacco-related deaths” in the U.S. has ever been produced by the government, academia or health organizations.  The percentage of deaths attributable to smoking, while undoubtedly large, is simply not known.

In reference 2 above, ACS attributes the false assertion to a New England Journal of Medicine article by tobacco researchers Michael Fiore, Steven Schroeder and Timothy Baker (here).  That article made virtually the same statement and cited a citizen petition submitted to the FDA in 2010 by Dr. Joel Nitzkin on behalf of the Tobacco Control Task Force of the American Association of Public Health Physicians (here).  Careful review of the Nitzkin filing reveals nothing to support the ACS or NEJM claim.

This falsehood can be corrected.  With some effort, the very small number of deaths from smokeless use and cigar/pipe smoking can be estimated from large federal datasets.  Government researchers and the ACS have the resources and should make this a priority, in order to provide a scientific foundation for FDA tobacco regulation.

Fabrication, or repetition of false statements, particularly by trusted authorities, organizations, and public figures, can result in widespread acceptance of myth as truth. Such cavalier inattention to fact is not acceptable in scientific discourse or public health policymaking, where actual lives are at stake (here).




Thursday, February 20, 2014

Tobacco Harm Reduction Endorsed in New England Journal of Medicine



In late January the New England Journal of Medicine published a ringing endorsement of tobacco harm reduction (here).  The authors of “Smoke, The Chief Killer – Strategies for Targeting Combustible Tobacco Use, are Michael Fiore and Timothy Baker from the University of Wisconsin, and Steven Schroeder from the University of California San Francisco.  In the past, they strongly opposed the adoption of safer cigarette substitutes.

Fiore and colleagues acknowledge that it’s the smoke that kills: “…research now quite clearly highlights the specific harms of combustible tobacco use (cigarette, pipe, and cigar smoking): given that up to 98% of tobacco-related deaths are attributable to combustible products, the net harms of these products, including harms from secondhand smoke, dwarf those of other forms of tobacco use (e.g., smokeless tobacco).” 

The authors are not referring to research that has just been published “now.”  Rather, the anti-tobacco establishment is just “now” acknowledging the fact that the risks of burning tobacco “dwarf” those of smoke-free forms.

Fiore et al. acknowledge the failure of all conventional cessation options: “…current smoking-cessation treatments fail for the majority of smokers who use them…”

More importantly, they move on to a surprising endorsement of smoke-free tobacco: “One opportunity afforded by today’s changing landscape lies in the diverse alternative nicotine delivery vehicles available to smokers.  Evidence shows that all the noncombustible delivery vehicles are substantially less dangerous than combustible tobacco products, though that’s not to say that they are all totally safe.  Noncombustible forms include multiple nicotine-replacement therapies (NRTs) as well as smokeless tobacco (e.g., snus) and the electronic cigarette.”

To be fair, Fiore and colleagues also devote a lot of attention to conventional approaches.  However, the change in attitude toward tobacco harm reduction is seen in their advice to clinicians:

1.  Advise patients that any tobacco product has risks, but that combustible tobacco is “by far the most harmful.”

2.  Counsel them to quit any tobacco product using the conventional methods.

3.  Try to get them to smoke fewer cigarettes.

4.  ADVISE PATIENTS WHO ASK ABOUT E-CIGARETTES THAT “THESE DEVICES ARE PROBABLY MUCH SAFER THAN COMBUSTIBLE TOBACCO PRODUCTS.” (emphasis added)

Finally, after expressing some e-cigarette gateway concerns, Fiore finishes with a strong message:

“Furthermore, we need to communicate intelligently about harm reduction: not all nicotine-containing products are equal, and the public health focus should be on eliminating combustible tobacco products, even if some people who give up combustibles will continue using FDA-approved medications, e-cigarettes, or smokeless tobacco products indefinitely…New approaches must be adopted if we are to dramatically reduce the harms of tobacco use in the United States over the next decade. To achieve this goal requires that we recognize the unequaled dangers resulting from combustible tobacco use.”

The commentary is accompanied by an audio interview with Matthew Myers (here), president of the Campaign for Tobacco-Free Kids and one of the most aggressive opponents of tobacco harm reduction.  While promoting cherished topics like increased state funding for tobacco control and an FDA-imposed menthol ban, Myers offers positive comments on tobacco harm reduction that are truly transformative.  Here are some excerpts:  

“We all continue to look for ways to get people to quit smoking cigarettes, the most dangerous product.  And e-cigarettes on the surface appear to hold potential to be another tool to do so.  One of the reasons that you see so many people interested in e-cigarettes is that, while current FDA-approved smoking cessation aids are shown to be effective and increase the likelihood of someone being able to quit, the success rates aren’t what anyone wants them to be.”

“But there will still be some patients, for certain, who, even after being provided that advice [on FDA-approved methods], they either don’t want to quit or they have been unable to quit…in those cases a physician should make an individual judgment whether or not smokeless tobacco or an e-cigarette might assist that individual.  In other words, we should keep trying, until that person actually quits.”

“What I would most like to see is the FDA take all the steps it can to maximize the extent to which it discourages the use of cigarettes, the most deadly products, and to encourage the use of FDA-approved cessation devices and other nicotine that is delivered safely without causing the kind of deaths and disease we’ve seen.”

With this change in disposition among long-term obstructionists, tobacco harm reduction is gaining real momentum.    

 

Wednesday, October 19, 2011

New England Journal of Medicine Promotes Failed Policies for Smoking Control

The New England Journal of Medicine on September 29 published a commentary (here) promoting “total abstinence” with behavioral therapy and medicines, a strategy that has failed to help over 90% of smokers who tried to quit. The article, by Michael Fiore and Timothy Baker of the University of Wisconsin, reflects the nation’s dual obsession with smoking as a disease and nicotine- and tobacco-abstinence as the only cure.

Fiore and Baker use the terms “smoking” and “tobacco use” synonymously. They write, “more than 30% of deaths from cancer, 90% of cases of COPD and 30% of cases of cardiovascular disease in the United States are attributed to tobacco use…Tobacco use remains the chief avoidable cause of death in the United States…”

That is demonstrably false. Tellingly, in the next sentence they drop the phrase “tobacco use” and correctly use the word “smoking.” I have previously described the unfortunate consequences of such deliberate misinformation (here).

While Fiore and Baker advise health professionals to “note the effectiveness of seven FDA-approved medications for smoking cessation,” they acknowledge that a meta-analysis documented that the abstinence rate for nicotine medicines was a mere 9% at six months -- a 91% failure rate. Despite these dismal statistics, Fiore and Baker use the words “effective” or “effectiveness” at least 10 times in describing quit-smoking medicines. Interestingly, they write that patients don’t use medicines because they believe them to be “dangerous” and “ineffective.” Although smokers incorrectly believe that nicotine medicines are dangerous, they are correct in believing that they are largely ineffective.

Anti-tobacco extremists and most journal editors continue to ignore the scientific evidence for tobacco harm reduction, but some medical journals are putting it front and center (here). It is unfortunate that the New England Journal of Medicine devoted 10 pages to a misleading abstinence-only screed.